Nocturnal intermittent hypoxemia: utility for the evaluation of severity sleep apnea and cardiovascular comorbidity

Introduction Sleep apnea-hypopnea syndrome (SAHS) is a complex public health problem causing increased risk of cardiovascular diseases. Traditionally, evaluation of the severity of the disease is based on Apnea-Hypopnea Index (AHI). Oxygen desaturation index (ODI) could be a good parameter for the e...

Full description

Saved in:
Bibliographic Details
Published in:Sleep medicine 2013-12, Vol.14, p.e67-e67
Main Authors: Baena, E. Mañas, Meneses, P. Lazo, Camara, J. Fernandez, Calvo, R. Esteban, Mazarro, A. Pedrera, Rodriguez, E. Perez
Format: Article
Language:English
Subjects:
Neurology
Sleep Medicine
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction Sleep apnea-hypopnea syndrome (SAHS) is a complex public health problem causing increased risk of cardiovascular diseases. Traditionally, evaluation of the severity of the disease is based on Apnea-Hypopnea Index (AHI). Oxygen desaturation index (ODI) could be a good parameter for the evaluation of the severity of SAHS and its potential cardiovascular consequences. TARGET: the aim of the present study was to examine the relationships between the overnight oxygen desaturation index (ODI), parameters sleep study and cardiovascular events in a sample of patients evaluated in the Unit Respiratory Sleep Disorders. Materials and methods We performed a retrospective study collecting data from 105 patients evaluated in the Unit Respiratory Sleep Disorders. In this study, diagnostic polygraphy recordings were retrospectively analysed. It was studied the correlation of ODI with AHI and the presence or absence of comorbidity, defining this as the presence of ischemic heart disease and / or arrhythmias and / or acute stroke. Results Among the 105 studied patients, 17(16%) had comorbidity. ODI values were correlated with AHI with a correlation coefficient of 0.87. There was a significant relationship between the severity of ODI and the presence of comorbidity ( p 0.038), and also a significant association between the AHI and the presence of comorbidity ( p 0.024). Conclusion ODI appears a good parameter to estimate the severity of OSA and may be associated with more prevalence of ischemic heart disease, arrhythmias and acute stroke. Acknowledgements Acknowledgements to authors of the study.
ISSN:1389-9457
1878-5506
DOI:10.1016/j.sleep.2013.11.130