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P10. Bone morphogenetic protein usage decreases the risk of reoperations after anterior cervical discectomy and fusion: a five-year survivorship analysis

Surgical intervention of the cervical spine is a challenging procedure that can present postoperative complications such as dysphagia, swelling, and reoperations. However, the risk of reoperation can possibly be mitigated with the use of biologics to enhance fusion. There is paucity in the literatur...

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Published in:The spine journal 2020-09, Vol.20 (9), p.S152-S152
Main Authors: Ahmad, Waleed, Bell, Joshua, Pierce, Katherine E., Naessig, Sara, Segreto, Frank A., Vira, Shaleen N., Lafage, Virginie, Paulino, Carl B., Schoenfeld, Andrew J., Diebo, Bassel G., Hassanzadeh, Hamid, Passias, Peter G.
Format: Article
Language:English
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Summary:Surgical intervention of the cervical spine is a challenging procedure that can present postoperative complications such as dysphagia, swelling, and reoperations. However, the risk of reoperation can possibly be mitigated with the use of biologics to enhance fusion. There is paucity in the literature on long-term incidence of reoperations after application of BMP during ACDF. To evaluate if bone morphogenetic protein usage during anterior cervical discectomy and fusion will decrease reoperation rates. Retrospective review of the PearlDiver database between 2006-2014. Matched cohort of 35,544 ACDF patients. Reoperations. Patients undergoing an anterior cervical discectomy and fusion between the years 2006-2014 were isolated in the PearlDiver database. Patients receiving BMP operatively and a control with no BMP were matched for baseline demographics including age, sex, and comorbidities. A Kaplan Meier Survival analysis assessed five-Year Reoperation-Free Survival between BMP patients and controls. Statistical significance was set to p0.05). Kaplan Meier survival analysis showed patients receiving BMP during cervical fusion were significantly more likely to remain reoperation free five years after index surgery (p
ISSN:1529-9430
1878-1632
DOI:10.1016/j.spinee.2020.05.408