Loading…

Synthesis of the tricyclic core structure of vindoline

Graphic An efficient synthesis of the core tricyclic structure ( 18 ) of vindoline has been achieved using the strategy, which features an intramolecular 1,3-dipolar cycloaddition of the azido dienone ( 12 ) to give aziridine ( 13 ) with complete region- and stereocontrol.

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2004-01, Vol.45 (5), p.919-921
Main Authors: Guo, Zihong, Schultz, Arthur G.
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Graphic An efficient synthesis of the core tricyclic structure ( 18 ) of vindoline has been achieved using the strategy, which features an intramolecular 1,3-dipolar cycloaddition of the azido dienone ( 12 ) to give aziridine ( 13 ) with complete region- and stereocontrol.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2003.11.115