1. Geriatric nutritional risk index can predict 90-day mortality in patients with osteoporotic vertebral fractures

• Published in: North American Spine Society journal (NASSJ) 2024-07, Vol.18, p.100339, Article 100339
• Main Author: Ito, Toshihiko
• Format: Article
• Language: English
• ISSN: 2666-5484; 2666-5484
• DOI: 10.1016/j.xnsj.2024.100339

Fragility fractures are common in elderly patients and are associated with high mortality and functional disability. The geriatric nutritional risk index (GNRI) is an objective nutritional status assessment tool to predict mortality risk in hospitalized patients. However, whether the GNRI reflects short-term mortality in fragility fracture patients is unclear. This study aimed to examine the nutritional status assessed by the GNRI in patients with fragility fractures and identify cut-off scores that predict mortality risk. N/A N/A N/A N/A Elderly fragility fracture patients in our hospital from 2021 to 2023 were retrospectively studied. A total of 56 patients (19 men and 37 women, mean age 83.2 ± 6.7 years) were included. All patients were followed up for more than 3 months. Clinical data were extracted from electronic medical records. Mortality within 90 days after admission was studied. GNRI was calculated for all patients on admission as 14.89 × serum albumin (g/dL) + 41.7 × BMI / 22. Using the recipient operating characteristic (ROC) curve, the area under the curve (AUC) that can predict mortality 90 days after admission and the optimal cut-off scores were calculated. The mean GNRI was 97.2 ± 9.2 (76.6-114.7). Three (5.2%) deaths occurred in the cohort; the ROC-AUC value was 0.85, and the cut-off GNRI was 95.6. Sensitivity and specificity were 100% and 64.2%, respectively. Our results show that nutritional status assessment using GNRI can help predict mortality within 90 days in elderly fragility fracture patients; GNRI can be considered a simple tool to predict mortality risk in fragility fracture patients. In addition, early detection of low nutritional status may improve nutritional status before fracture, reducing mortality risk. This abstract does not discuss or include any applicable devices or drugs.