Optimal Dietary Ferulic Acid for Suppressing the Obesity-Related Disorders in Leptin-Deficient Obese C57BL/6J-ob/ob Mice

Ferulic acid (FA) is a major polyphenolic compound and has been shown to improve the glucose and lipid homeostasis in high-fat diet-induced obese mice. Here, we found the optimal level of dietary FA to ameliorate obesity and obesity-correlated disorders, and identified the responses of gut microbiot...

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Bibliographic Details
Published in:Journal of agricultural and food chemistry 2019-04, Vol.67 (15), p.4250-4258
Main Authors: Wang, Weiwei, Pan, Yiou, Wang, Li, Zhou, Hang, Song, Ge, Wang, Yongwei, Liu, Jianxue, Li, Aike
Format: Article
Language:English
Subjects:
Adipose Tissue - metabolism
animal disease models
Animals
Bacteria - classification
Bacteria - genetics
Bacteria - isolation & purification
Coumaric Acids - metabolism
feed conversion
Female
ferulic acid
Gastrointestinal Microbiome
glucose
high fat diet
homeostasis
Humans
intestinal microorganisms
Intestines - microbiology
Leptin - deficiency
Leptin - genetics
lipids
Male
Mice
Mice, Inbred C57BL
Mice, Obese
obesity
Obesity - diet therapy
Obesity - genetics
Obesity - metabolism
Obesity - microbiology
obesity-related diseases
weight control
white adipose tissue
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