Understanding the Interaction of Pyrimidine-Based Model Compounds of DNA and RNA with Magnesium Chloride in Aqueous Solutions via Thermodynamic, Transport, and Spectroscopic Studies

Densities, viscosities, and molar enthalpies of dilutions were obtained for bases of nucleic acids in magnesium chloride (MgCl2) aqueous solutions over a temperature range of 288.15–318.15 K. From these data, standard molar volume, V 2,ϕ°, viscosity B-coefficient, and standard molar enthalpy of dilu...

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Bibliographic Details
Published in:Journal of chemical and engineering data 2023-12, Vol.68 (12), p.3000-3020
Main Authors: Kaur, Navalpreet, Kaur, Harjinder, Aggarwal, Neha, Banipal, Tarlok S., Arti, Sonika
Format: Article
Language:English
Subjects:
Thermophysical and Thermochemical Properties
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Summary:Densities, viscosities, and molar enthalpies of dilutions were obtained for bases of nucleic acids in magnesium chloride (MgCl2) aqueous solutions over a temperature range of 288.15–318.15 K. From these data, standard molar volume, V 2,ϕ°, viscosity B-coefficient, and standard molar enthalpy of dilution (Δm,dil H°) values were obtained. The results suggest the predominance of ion–hydrophilic interactions over ion–hydrophobic interactions occurring in these solutions. It was observed that increasing the MgCl2 concentration leads to enhanced solvation due to ion–hydrophilic interactions. UV–visible and nuclear magnetic resonance spectroscopic studies further explain the solute–MgCl2 interactions via the dehydration effect. The present results were compared with those reported earlier in the presence of other cosolutes.
ISSN:0021-9568
1520-5134
DOI:10.1021/acs.jced.3c00282