A Highly Active Catalyst System for Suzuki–Miyaura Coupling of Aryl Chlorides

A series of new Pd­(II) complexes with simple structures were designed and synthesized for Suzuki–Miyaura coupling reactions of aryl chlorides. The new Pd­(II) complexes contain bidentate amine ligands, and their structures were characterized by single-crystal X-ray diffraction. They are highly effi...

Full description

Saved in:
Bibliographic Details
Published in:Organometallics 2019-04, Vol.38 (7), p.1459-1467
Main Authors: Liu, Guiyan, Han, Fangwai, Liu, Chengxin, Wu, Hongli, Zeng, Yongfei, Zhu, Rongjiao, Yu, Xia, Rao, Shuang, Huang, Genping, Wang, Jianhui
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A series of new Pd­(II) complexes with simple structures were designed and synthesized for Suzuki–Miyaura coupling reactions of aryl chlorides. The new Pd­(II) complexes contain bidentate amine ligands, and their structures were characterized by single-crystal X-ray diffraction. They are highly efficient for Suzuki–Miyaura coupling reactions of aryl chlorides with low catalyst loadings (0.01 mol %) in aqueous media at room temperature. Two possible reaction pathways involving a PdII/0/II and a PdII/IV/II catalytic cycle are proposed, and the mechanism was further investigated using density functional theory (DFT) calculations.
ISSN:0276-7333
1520-6041
DOI:10.1021/acs.organomet.8b00883