Spectrophotometric Determination of the Acidity Constants of Some Oxime-Based α-Nucleophiles

The acidity constants (pK a) of oxime group containing nucleophiles like pralidoxime, butane 2,3-dione monoxime (BDMO), and some novel oxime-based functionalized nucleophiles, i.e., 3- and 4-hydroxyiminomethyl-1-alkylpyridinium bromides, have been determined spectrophotometrically at 27 °C in pure w...

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Bibliographic Details
Published in:Journal of chemical and engineering data 2010-03, Vol.55 (3), p.1153-1157
Main Authors: Tiwari, Shuchi, Ghosh, Kallol K, Marek, Jan, Kuca, Kamil
Format: Article
Language:English
Subjects:
Chemistry
Exact sciences and technology
Heterocyclic compounds
Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings
Organic chemistry
Preparations and properties
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Summary:The acidity constants (pK a) of oxime group containing nucleophiles like pralidoxime, butane 2,3-dione monoxime (BDMO), and some novel oxime-based functionalized nucleophiles, i.e., 3- and 4-hydroxyiminomethyl-1-alkylpyridinium bromides, have been determined spectrophotometrically at 27 °C in pure water and in a 50% (v/v) water−acetonitrile mixture, respectively. An effect of surfactant concentration on the pK a of pralidoxime has also been studied. It has been found that the pK a of pralidoxime was not affected by surfactant concentration.
ISSN:0021-9568
1520-5134
DOI:10.1021/je9005773