Telluroxides Exhibit Hydrolysis Capacity

It has long been known that tellurium compounds are rather toxic to living organisms, and tellurium has not been found in natural biomacromolecules to date. The principles of telluride toxicity in biological processes are still controversial partly because of the lack of information on the biochemic...

Full description

Saved in:
Bibliographic Details
Published in:Journal of organic chemistry 2007-01, Vol.72 (2), p.606-609
Main Authors: Dong, Zeyuan, Li, Xiangqiu, Liang, Kai, Mao, Shizhong, Huang, Xin, Yang, Bing, Xu, Jiayun, Luo, Guimin, Shen, Jiacong
Format: Article
Language:English
Subjects:
Chemistry
Exact sciences and technology
Organic chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:It has long been known that tellurium compounds are rather toxic to living organisms, and tellurium has not been found in natural biomacromolecules to date. The principles of telluride toxicity in biological processes are still controversial partly because of the lack of information on the biochemical features of tellurium. In this contribution, we report our finding for the first time that telluroxides exhibit hydrolysis capacity. For instance, 6,6‘-telluroxy-bis(6-deoxy-β-cyclodextrin) acts as a hydrolase mimic and shows a significant rate acceleration of 106 000 for the hydrolysis of 4,4‘-dinitrodiphenyl carbonate.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo0620922