A draft UAE-based Arab pangenome reference

Pangenomes provide a robust and comprehensive portrayal of genetic diversity in humans, but Arab populations remain underrepresented. We present a preliminary UAE-based Arab Pangenome Reference (UPR) utilizing 53 individuals of diverse Arab ethnicities residing in the United Arab Emirates. We assemb...

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Published in:Nature communications 2025-07, Vol.16 (1), p.6747-17, Article 6747
Main Authors: Nassir, Nasna, Almarri, Mohamed A., Kumail, Muhammad, Mohamed, Nesrin, Balan, Bipin, Hanif, Shehzad, AlObathani, Maryam, Jamalalail, Bassam, Elsokary, Hanan, Kondaramage, Dasuki, Shiyas, Suhana, Kosaji, Noor, Satsangi, Dharana, Abdelmotagali, Madiha Hamdi Saif, Abou Tayoun, Ahmad, Ahmed, Olfat Zuhair Salem, Youssef, Douaa Fathi, Suwaidi, Hanan Al, Albanna, Ammar, S Du Plessis, Stefan, Khansaheb, Hamda Hassan, Alsheikh-Ali, Alawi, Uddin, Mohammed
Format: Article
Language:English
Subjects:
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Arab people
Arabs - genetics
Assemblies
Cardiovascular disease
Datasets
Diabetes
Gene Duplication
Genetic diversity
Genetic Variation
Genetics, Population
Genome, Human - genetics
Genomes
Haplotypes
Humanities and Social Sciences
Humans
multidisciplinary
Population
Population genetics
Populations
Principal components analysis
Ribosomal DNA
Science
Science (multidisciplinary)
TATA-binding protein
United Arab Emirates
Y chromosomes
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