Dietary arginine affects the insulin signaling pathway, glucose metabolism and lipogenesis in juvenile blunt snout bream Megalobrama amblycephala

This study evaluated the mechanisms governing insulin resistance, glucose metabolism and lipogenesis in juvenile fish fed with graded levels of dietary arginine. The results showed that, compared with the control group (0.87%), 2.31% dietary arginine level resulted in the upregulation of the relativ...

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Bibliographic Details
Published in:	Scientific reports 2017-08, Vol.7 (1), p.7864-11, Article 7864
Main Authors:	Liang, Hualiang, Habte-Tsion, Habte-Michael, Ge, Xianping, Ren, Mingchun, Xie, Jun, Miao, Linghong, Zhou, Qunlan, Lin, Yan, Pan, Wenjing
Format:	Article
Language:	English
Subjects:	1-Phosphatidylinositol 3-kinase 38 38/77 631/337/572/2102 631/45/221 Adipogenesis AKT protein Animals Arginine Arginine - administration & dosage Arginine - pharmacology Cyprinidae - genetics Cyprinidae - metabolism Dietary Supplements Fish Proteins - genetics Fish Proteins - metabolism Gene expression Gene Expression - drug effects Gluconeogenesis Gluconeogenesis - drug effects Gluconeogenesis - genetics Glucose Glucose - metabolism Glucose transporter Glycolysis Humanities and Social Sciences Insulin Insulin - metabolism Insulin receptor substrate 1 Insulin Receptor Substrate Proteins - genetics Insulin Receptor Substrate Proteins - metabolism Insulin Resistance Lipogenesis Lipogenesis - drug effects Metabolism multidisciplinary Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - metabolism Science Science (multidisciplinary) Signal transduction Signal Transduction - drug effects
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