Innate immune responses at the asymptomatic stage of influenza A viral infections of Streptococcus pneumoniae colonized and non-colonized mice

Seasonal Influenza A virus (IAV) infections can promote dissemination of upper respiratory tract commensals such as Streptococcus pneumoniae to the lower respiratory tract resulting in severe life-threatening pneumonia. Here, we aimed to compare innate immune responses in the lungs of healthy coloni...

Full description

Saved in:

Bibliographic Details
Published in:	Scientific reports 2021-10, Vol.11 (1), p.20609-13, Article 20609
Main Authors:	Cuypers, Fabian, Schäfer, Alexander, Skorka, Sebastian B., Surabhi, Surabhi, Tölken, Lea A., Paulikat, Antje D., Kohler, Thomas P., Otto, Saskia A., Mettenleiter, Thomas C., Hammerschmidt, Sven, Blohm, Ulrike, Siemens, Nikolai
Format:	Article
Language:	English
Subjects:	631/250 631/250/2504 631/250/254 631/250/255 631/250/262 631/326 631/326/41 631/326/41/2533 631/326/596 631/326/596/1578 Animals Asymptomatic Bacterial diseases Bacterial infections Carrier State - immunology CCR2 protein Coinfection - virology Commensals Cytokines Cytokines - metabolism Disease Models, Animal Female Flow cytometry Humanities and Social Sciences Humans Immune response Immunity, Innate - immunology Inflammation Influenza Influenza A Influenza A virus - immunology Influenza A virus - pathogenicity Influenza A Virus, H1N1 Subtype - immunology Influenza A Virus, H1N1 Subtype - pathogenicity Innate immunity Leukocytes (neutrophilic) Lung - immunology Macrophages - immunology Mice Mice, Inbred C57BL Monocyte chemoattractant protein 1 Monocytes multidisciplinary Neutrophils - metabolism Orthomyxoviridae Infections - immunology Orthomyxoviridae Infections - virology Phenotypes Pneumococcal Infections - complications Pneumococcal Infections - immunology Pneumonia Pneumonia, Bacterial Pneumonia, Pneumococcal - immunology Primary Cell Culture Respiratory tract Respiratory Tract Infections - immunology Respiratory Tract Infections - virology Science Science (multidisciplinary) Streptococcus infections Streptococcus pneumoniae Streptococcus pneumoniae - pathogenicity Viral infections
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!