Obesity and accelerated epigenetic aging in a high-risk cohort of children

New insights into mechanisms linking obesity to poor health outcomes suggest a role for cellular aging pathways, casting obesity as a disease of accelerated biological aging. Although obesity has been linked to accelerated epigenetic aging in middle-aged adults, the impact during childhood remains u...

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Bibliographic Details
Published in:Scientific reports 2022-05, Vol.12 (1), p.8328-9, Article 8328
Main Authors: Etzel, Laura, Hastings, Waylon J., Hall, Molly A., Heim, Christine M., Meaney, Michael J., Noll, Jennie G., O’Donnell, Kieran J., Pokhvisneva, Irina, Rose, Emma J., Schreier, Hannah M. C., Shenk, Chad E., Shalev, Idan
Format: Article
Language:English
Subjects:
692/308/3187
692/699/2743/393
Adolescent
Adult
Aging
Aging - genetics
Body mass index
Child
Children
DNA Methylation
Epigenesis, Genetic
Epigenetics
Generalized linear models
Health risks
Humanities and Social Sciences
Humans
Leukocytes
Middle Aged
Morbidity
Mortality risk
multidisciplinary
Obesity
Obesity - genetics
Prospective Studies
Science
Science (multidisciplinary)
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