Palladium-catalyzed intermolecular carbonylative cross-coupling of heteroaryl C(sp 2 )-H bonds with amines: an efficient strategy for oxidative aminocarbonylation of azoles

An efficient palladium-catalyzed oxidative aminocarbonylation of azoles has been developed. This system allows for intermolecular carbonylative cross-coupling of aromatic C(sp )-H bonds with simple amines, which has often been asked for, but has not been realized so far. It provides a straightforwar...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2017, Vol.53 (51), p.6914-6917
Main Authors: Xing, Qi, Lv, Hui, Xia, Chungu, Li, Fuwei
Format: Article
Language:English
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Summary:An efficient palladium-catalyzed oxidative aminocarbonylation of azoles has been developed. This system allows for intermolecular carbonylative cross-coupling of aromatic C(sp )-H bonds with simple amines, which has often been asked for, but has not been realized so far. It provides a straightforward approach to a variety of azol-2-amides.
ISSN:1359-7345
1364-548X
DOI:10.1039/c7cc03274a