Effectiveness of Petrosectomy in Temporal Bone Malignant Invasion

• Main Authors: Wierzbicka, Malgorzata, Szyfter, W., , Tkopeæ
• Format: Conference Proceeding
• Language: English
• ISSN: 2193-6331; 2193-634X
• DOI: 10.1055/s-0034-1383935

Squamous cell carcinoma (SCC) of temporal bone derived from external auditory meatus or middle ear is rare, more frequent being the cancers of skin and parotid invading the temporal bone. The aim of this study was to present outcomes of extensive surgery: lateral, subtotal, total petrosectomies in patients with temporal bone invasion in particular primaries, with special regard to survival in advanced stages of diseases. Retrospective analysis of 20 consecutive patients, 11 with temporal bone SCC and 9 with parotid gland primary with lateral skull base infiltration, treated by means of total, subtotal or lateral petrosectomy at the university department of otolaryngology, tertiary referral center between January, 2006 and December, 2010. Results : Overall 14/20 patients (70%) were alive at the time of analysis, follow-up ranged from 36 to 60 months. Seven patients developed relapse (four local, three distant metastases), all except one died. Median time to relapse was 6 months (range,2-24 months), time of survival with relapse was 6 month (range,1-17 months). The 3-year disease free and overall survival was 65 and 68.42%, respectively. Five patients have been observed for 4 years and two patients for 5 years without recurrence. The differences between temporal bone and parotid group survival were not statistically significant ( p = 0.20216). For whole group impact for outcome had involvement of dura (five patients, p = 0.04828) and positive resection margins (six patients, p = 0.00697).