Development of Chiral Catalysts by Asymmetric Activation for Highly Enantioselective Diethylzinc Addition to Imines

Abstract Based on the asymmetric activation concept, a library of chiral zinc complexes in situ formed by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asymmetric addition of diethylzinc to N-acylimines. In...

Full description

Saved in:
Bibliographic Details
Published in:Synlett 2005-03, Vol.2005 (4), p.615-618
Main Authors: Zhang, Hai-Le, Liu, Hua, Cui, Xin, Mi, Ai-Qiao, Jiang, Yao-Zhong, Gong, Liu-Zhu
Format: Article
Language:English
Subjects:
letter
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 618
container_issue 4
container_start_page 615
container_title Synlett
container_volume 2005
creator Zhang, Hai-Le
Liu, Hua
Cui, Xin
Mi, Ai-Qiao
Jiang, Yao-Zhong
Gong, Liu-Zhu
description Abstract Based on the asymmetric activation concept, a library of chiral zinc complexes in situ formed by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asymmetric addition of diethylzinc to N-acylimines. In the presence of 10 mol% L3ZNA1, high enantioselectivities and yields were provided for a wide range of aromatic imines in 1,2-dichloroethane at -25 °C.
doi_str_mv 10.1055/s-2005-863709
format article
fullrecord <record><control><sourceid>thieme_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1055_s_2005_863709</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1055_s_2005_863709</sourcerecordid><originalsourceid>FETCH-LOGICAL-c230t-d153a7ce8deb61a9cdab5f98752eb71112d5c78c91aa62695738298ab3f630373</originalsourceid><addsrcrecordid>eNp1kLFOwzAQhi0EEqUwsvsBMNhxHcdjlZa2UiUWmC3HuRBXTlLZplJ4elLKynTSf99_On0IPTL6zKgQL5FklApS5FxSdYVmbMHlFKn8Gs2o4jkRGVvcorsYD5SyRaHoDMUVnMAPxw76hIcGl60LxuPSJOPHmCKuRryMY9dBCs7ipU3uZJIbetwMAW_dZ-tHvO5NP2URPJz3gFcOUjv6b9dPlbp2v4U04F3neoj36KYxPsLD35yjj9f1e7kl-7fNrlzuic04TaRmghtpoaihyplRtjaVaFQhRQaVZIxltbCysIoZk2e5EpIXmSpMxZucUy75HJHLXRuGGAM0-hhcZ8KoGdVnYzrqszF9MTbxTxc-tQ460IfhK_TTg__gPxCybk8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Development of Chiral Catalysts by Asymmetric Activation for Highly Enantioselective Diethylzinc Addition to Imines</title><source>Thieme - Connect here FIRST to enable access</source><creator>Zhang, Hai-Le ; Liu, Hua ; Cui, Xin ; Mi, Ai-Qiao ; Jiang, Yao-Zhong ; Gong, Liu-Zhu</creator><creatorcontrib>Zhang, Hai-Le ; Liu, Hua ; Cui, Xin ; Mi, Ai-Qiao ; Jiang, Yao-Zhong ; Gong, Liu-Zhu</creatorcontrib><description>Abstract Based on the asymmetric activation concept, a library of chiral zinc complexes in situ formed by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asymmetric addition of diethylzinc to N-acylimines. In the presence of 10 mol% L3ZNA1, high enantioselectivities and yields were provided for a wide range of aromatic imines in 1,2-dichloroethane at -25 °C.</description><identifier>ISSN: 0936-5214</identifier><identifier>EISSN: 1437-2096</identifier><identifier>DOI: 10.1055/s-2005-863709</identifier><language>eng</language><subject>letter</subject><ispartof>Synlett, 2005-03, Vol.2005 (4), p.615-618</ispartof><rights>Georg Thieme Verlag Stuttgart · New York</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2005-863709.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><linktohtml>$$Uhttps://www.thieme-connect.de/products/ejournals/html/10.1055/s-2005-863709$$EHTML$$P50$$Gthieme$$H</linktohtml><link.rule.ids>314,776,780,3004,3005,27901,27902,54534,54535</link.rule.ids></links><search><creatorcontrib>Zhang, Hai-Le</creatorcontrib><creatorcontrib>Liu, Hua</creatorcontrib><creatorcontrib>Cui, Xin</creatorcontrib><creatorcontrib>Mi, Ai-Qiao</creatorcontrib><creatorcontrib>Jiang, Yao-Zhong</creatorcontrib><creatorcontrib>Gong, Liu-Zhu</creatorcontrib><title>Development of Chiral Catalysts by Asymmetric Activation for Highly Enantioselective Diethylzinc Addition to Imines</title><title>Synlett</title><addtitle>Synlett</addtitle><description>Abstract Based on the asymmetric activation concept, a library of chiral zinc complexes in situ formed by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asymmetric addition of diethylzinc to N-acylimines. In the presence of 10 mol% L3ZNA1, high enantioselectivities and yields were provided for a wide range of aromatic imines in 1,2-dichloroethane at -25 °C.</description><subject>letter</subject><issn>0936-5214</issn><issn>1437-2096</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNp1kLFOwzAQhi0EEqUwsvsBMNhxHcdjlZa2UiUWmC3HuRBXTlLZplJ4elLKynTSf99_On0IPTL6zKgQL5FklApS5FxSdYVmbMHlFKn8Gs2o4jkRGVvcorsYD5SyRaHoDMUVnMAPxw76hIcGl60LxuPSJOPHmCKuRryMY9dBCs7ipU3uZJIbetwMAW_dZ-tHvO5NP2URPJz3gFcOUjv6b9dPlbp2v4U04F3neoj36KYxPsLD35yjj9f1e7kl-7fNrlzuic04TaRmghtpoaihyplRtjaVaFQhRQaVZIxltbCysIoZk2e5EpIXmSpMxZucUy75HJHLXRuGGAM0-hhcZ8KoGdVnYzrqszF9MTbxTxc-tQ460IfhK_TTg__gPxCybk8</recordid><startdate>20050304</startdate><enddate>20050304</enddate><creator>Zhang, Hai-Le</creator><creator>Liu, Hua</creator><creator>Cui, Xin</creator><creator>Mi, Ai-Qiao</creator><creator>Jiang, Yao-Zhong</creator><creator>Gong, Liu-Zhu</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20050304</creationdate><title>Development of Chiral Catalysts by Asymmetric Activation for Highly Enantioselective Diethylzinc Addition to Imines</title><author>Zhang, Hai-Le ; Liu, Hua ; Cui, Xin ; Mi, Ai-Qiao ; Jiang, Yao-Zhong ; Gong, Liu-Zhu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c230t-d153a7ce8deb61a9cdab5f98752eb71112d5c78c91aa62695738298ab3f630373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>letter</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Hai-Le</creatorcontrib><creatorcontrib>Liu, Hua</creatorcontrib><creatorcontrib>Cui, Xin</creatorcontrib><creatorcontrib>Mi, Ai-Qiao</creatorcontrib><creatorcontrib>Jiang, Yao-Zhong</creatorcontrib><creatorcontrib>Gong, Liu-Zhu</creatorcontrib><collection>CrossRef</collection><jtitle>Synlett</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Hai-Le</au><au>Liu, Hua</au><au>Cui, Xin</au><au>Mi, Ai-Qiao</au><au>Jiang, Yao-Zhong</au><au>Gong, Liu-Zhu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development of Chiral Catalysts by Asymmetric Activation for Highly Enantioselective Diethylzinc Addition to Imines</atitle><jtitle>Synlett</jtitle><addtitle>Synlett</addtitle><date>2005-03-04</date><risdate>2005</risdate><volume>2005</volume><issue>4</issue><spage>615</spage><epage>618</epage><pages>615-618</pages><issn>0936-5214</issn><eissn>1437-2096</eissn><abstract>Abstract Based on the asymmetric activation concept, a library of chiral zinc complexes in situ formed by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asymmetric addition of diethylzinc to N-acylimines. In the presence of 10 mol% L3ZNA1, high enantioselectivities and yields were provided for a wide range of aromatic imines in 1,2-dichloroethane at -25 °C.</abstract><doi>10.1055/s-2005-863709</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0936-5214
ispartof Synlett, 2005-03, Vol.2005 (4), p.615-618
issn 0936-5214
1437-2096
language eng
recordid cdi_crossref_primary_10_1055_s_2005_863709
source Thieme - Connect here FIRST to enable access
subjects letter
title Development of Chiral Catalysts by Asymmetric Activation for Highly Enantioselective Diethylzinc Addition to Imines
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T14%3A39%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-thieme_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Development%20of%20Chiral%20Catalysts%20by%20Asymmetric%20Activation%20for%20Highly%20Enantioselective%20Diethylzinc%20Addition%20to%20Imines&rft.jtitle=Synlett&rft.au=Zhang,%20Hai-Le&rft.date=2005-03-04&rft.volume=2005&rft.issue=4&rft.spage=615&rft.epage=618&rft.pages=615-618&rft.issn=0936-5214&rft.eissn=1437-2096&rft_id=info:doi/10.1055/s-2005-863709&rft_dat=%3Cthieme_cross%3E10_1055_s_2005_863709%3C/thieme_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c230t-d153a7ce8deb61a9cdab5f98752eb71112d5c78c91aa62695738298ab3f630373%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true