Synthesis of the C19-C34 Segment of Amphidinolide C

Abstract The synthesis of the C19-C34 segment of amphidinolide C is described. The key steps include the Mioskowski’s Lewis acid catalyzed epoxide opening with the alcohol, ring-closing metathesis, Wittig reaction, and Nozaki-Hiyama-Kishi coupling reaction.

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Published in:Synlett 2007-03, Vol.2007 (4), p.0567-0570
Main Authors: Mohapatra, Debendra K., Rahaman, Hasibur, Chorghade, Mukund S., Gurjar, Mukund K.
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creator Mohapatra, Debendra K.
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Chorghade, Mukund S.
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description Abstract The synthesis of the C19-C34 segment of amphidinolide C is described. The key steps include the Mioskowski’s Lewis acid catalyzed epoxide opening with the alcohol, ring-closing metathesis, Wittig reaction, and Nozaki-Hiyama-Kishi coupling reaction.
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title Synthesis of the C19-C34 Segment of Amphidinolide C
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