Enantioselective Total Synthesis of (-)-trans-Dendrochrysine via a Ring-Rearrangement Metathesis Approach

Abstract The enantioselective total synthesis of the dipyrrolidine alkaloid (-)-TRANS-dendrochrysine was accomplished in 18 steps starting from tropone. The key step was a ring-rearrangement ­metathesis for the construction of the bisheterocyclic skeleton of the natural product in a single step.

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Bibliographic Details
Published in:Synlett 2007-10, Vol.2007 (16), p.2599-2601
Main Authors: Dochnahl, Maximilian, Schulz, Sabrina Renate, Blechert, Siegfried
Format: Article
Language:English
Subjects:
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Summary:Abstract The enantioselective total synthesis of the dipyrrolidine alkaloid (-)-TRANS-dendrochrysine was accomplished in 18 steps starting from tropone. The key step was a ring-rearrangement ­metathesis for the construction of the bisheterocyclic skeleton of the natural product in a single step.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2007-986672