N,N’-Carbonyldiimidazole as a reagent of choice for the synthesis of thienyl-substituted pyrrolidine-2,5-diones

N- tert-Butyloxycarbonylamino-3-[ Z-α-(2,5-dimethyl-3-thienyl)ethylidene]-4-isopropylidenepyrrolidine-2,5-dione was prepared in 80% yield from the corresponding isomeric hydrazidic acids using N,N’-carbonyldiimidazole, whereas a number of other cyclisation reagents were ineffective.

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Bibliographic Details
Published in:Mendeleev communications 2003, Vol.13 (4), p.192-193
Main Authors: Krayushkin, Mikhail M., Stoyanovich, Felix M., Shorunov, Sergei V.
Format: Article
Language:English
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Summary:N- tert-Butyloxycarbonylamino-3-[ Z-α-(2,5-dimethyl-3-thienyl)ethylidene]-4-isopropylidenepyrrolidine-2,5-dione was prepared in 80% yield from the corresponding isomeric hydrazidic acids using N,N’-carbonyldiimidazole, whereas a number of other cyclisation reagents were ineffective.
ISSN:0959-9436
1364-557X
DOI:10.1070/MC2003v013n04ABEH001761