Piece by piece: Building a ribozyme

The ribosome and RNase P are cellular ribonucleoprotein complexes that perform peptide bond synthesis and phosphodiester bond cleavage, respectively. Both are ancient biological assemblies that were already present in the last universal common ancestor of all life. The large subunit rRNA in the ribo...

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Bibliographic Details
Published in:The Journal of biological chemistry 2020-02, Vol.295 (8), p.2313-2323
Main Authors: Gray, Michael W., Gopalan, Venkat
Format: Article
Language:English
Subjects:
enzyme catalysis
evolution
Evolution, Molecular
JBC Reviews
Models, Molecular
ribonuclease P (RNase P)
Ribonuclease P - metabolism
ribonucleoprotein complex
ribosome
ribozyme (catalytic RNA) (RNA enzyme)
RNA, Catalytic - metabolism
RNA, Ribosomal - metabolism
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