Prognostic significance of fragmented QRS in acute pulmonary embolism

Background Presence of fragmented QRS (fQRS) complex in a 12-lead electrocardiogram (ECG) has been shown to represent alternation of myocardial activation owing to myocardial scar. The aim of this study was to investigate whether presence of fQRS complex predicts in-hospital and longterm mortality i...

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Bibliographic Details
Published in:Acta Cardiologica 2016-08, Vol.71 (4), p.443-448
Main Authors: Karaca, Mehmet, Tatlisu, Mustafa Adem, Ozcan, Kazim Serhan, Gungor, Barɪs, Bozbeyoglu, Emrah, Yildirimturk, Ozlem, Arugaslan, Emre, Zengin, Ahmet, Calik, Ali Nazmi, Nurkalem, Zekeriya, Cam, Nese
Format: Article
Language:English
Subjects:
Acute pulmonary embolism
Aged
Aged, 80 and over
Computed Tomography Angiography - methods
Electrocardiography - methods
Female
Follow-Up Studies
Hospital Mortality
Humans
Long Term Adverse Effects - mortality
Male
Middle Aged
mortality
Predictive Value of Tests
Prognosis
Proportional Hazards Models
Pulmonary Artery - diagnostic imaging
Pulmonary Embolism - diagnosis
Pulmonary Embolism - mortality
QRS fragmentation
Risk Assessment
Turkey - epidemiology
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Summary:Background Presence of fragmented QRS (fQRS) complex in a 12-lead electrocardiogram (ECG) has been shown to represent alternation of myocardial activation owing to myocardial scar. The aim of this study was to investigate whether presence of fQRS complex predicts in-hospital and longterm mortality in patients with acute pulmonary embolism (APE). Methods This study included 186 consecutive patients with APE. Computed tomography pulmonary angiography (CTPA) was used to diagnose APE. ECG was obtained immediately after admission. Results Patients were divided into two groups: patients who had fQRS on their ECG (n = 52), and patients who did not have fQRS on their ECG (n = 134). The fQRS was associated with not only in-hospital mortality (P =0.02) but also long-term mortality (P =0.01). Furthermore, the fQRS was found to be a significant predictor of in-hospital and long-term mortality in multivariable Cox analyses. Conclusion In this study, fQRS was found to be predictors of both in-hospital and long-term mortality. Electrocardiography can be used to detect high-risk patients in APE; moreover, it bears little risk, is inexpensive, and easy to perform.
ISSN:0001-5385
1784-973X
0373-7934
DOI:10.1080/AC.71.4.3159697