Catalytic Asymmetric Oxidation of Alkyl Aryl Sulfides Mediated by a Series of Chiral N-Alkyl-1,2-diphenylaminoethanol/Titanium/Water Complexes

A series of chiral N-alkyl-1,2-diphenylaminoethanol/titanium/water complexes were investigated as potential efficient catalyst for the enantioselective oxidation of alkyl aryl sulfides. The structure of the aminoethanols strongly influenced on the reactivity and enantioselectivity. Using (1S,2S)-N-m...

Full description

Saved in:
Bibliographic Details
Published in:Synthetic communications 2003-01, Vol.33 (16), p.2793-2801
Main Authors: Peng, YunGui, Feng, XiaoMing, Cui, Xin, Jiang, YaoZhong, Choi, Michael C. K., Chan, Albert S. C.
Format: Article
Language:English
Subjects:
Aminoethanol
Asymmetric catalysis
Chiral sulfoxide
Titanium(IV) complexes
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A series of chiral N-alkyl-1,2-diphenylaminoethanol/titanium/water complexes were investigated as potential efficient catalyst for the enantioselective oxidation of alkyl aryl sulfides. The structure of the aminoethanols strongly influenced on the reactivity and enantioselectivity. Using (1S,2S)-N-methyl-1,2-diphenylaminoethanol (6) as ligand in oxidation of methyl phenyl sulfide, gave (S)-sulfoxide with moderate yield and ee.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-120022167