Binary and Mixed Ligand Complexes of Nifuroxime, Spectral, and Thermal Studies

• Published in: Synthesis and reactivity in inorganic and metal-organic chemistry 2003-01, Vol.33 (7), p.1171-1186
• Main Author: El-Said, Asma I.
• Format: Article
• Language: English
• Subjects: Amino acids; Metal oximate; Nifuroxime
• ISSN: 0094-5714; 1532-2440
• DOI: 10.1081/SIM-120023485

Complexes of nifuroxime (anti-5-nitro-2-furfuraldoxime, 5N-FDH) with Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), La(III) and UO 2 (VI) have been prepared and characterized by elemental analyses, conductivity measurements, spectral and thermal studies. Also, some mixed nifuroximato-phenylalaninato,-tyrosinato or -methioninatonickel(II) complexes have been prepared and characterized by the previous methods. The complexes have the general formulae: [M(5N-FD) 2 ·mH 2 O] n ; [La(5N-FD)(OOCCH 3 ) 2 (H 2 O) 2 ] 2 ; [UO 2 (5N-FD) 2 ]·2H 2 O and [Ni(5N-FD)(L)]·H 2 O where M = Mn(II) Co(II), Ni(II), Cu(II), Zn(II) or Cd(II); m = 0 for M = Mn(II), m = 1 for M = Co(II), Ni(II) or Cd(II) and m = 2 for M = Cu(II) or Zn(II); L = phenylalaninate, tyrosinate or methioninate. All complexes were isolated at pH 6 using NH 4 OH solution. Nifuroxime acts as a uninegative ligand in all complexes with various modes of coordination. Thermogravimetric studies show a rapid decomposition stage for all the complexes accompanied by other slow stages; the final product of all complexes is the metal oxide.