NF-κB factors cooperate with Su(Hw)/E4F1 to balance Drosophila/human immune responses via modulating dynamic expression of miR-210

MicroRNAs (miRNAs) play crucial regulatory roles in controlling immune responses, but their dynamic expression mechanisms are poorly understood. Here, we firstly confirm that the conserved miRNA miR-210 negatively regulates innate immune responses of Drosophila and human via targeting Toll and TLR6,...

Full description

Saved in:

Bibliographic Details
Published in:	Nucleic acids research 2024-07, Vol.52 (12), p.6906-6927
Main Authors:	Zhou, Hongjian, Huang, Yu, Jia, Chaolong, Pang, Yujia, Liu, Li, Xu, Yina, Jin, Ping, Qian, Jinjun, Ma, Fei
Format:	Article
Language:	English
Subjects:	Animals Cell Line Drosophila - genetics Drosophila - immunology Drosophila melanogaster - genetics Drosophila melanogaster - immunology Drosophila Proteins - genetics Drosophila Proteins - metabolism Gene Expression Regulation Gene regulation, Chromatin and Epigenetics Humans Immunity, Innate - genetics MicroRNAs - genetics MicroRNAs - metabolism NF-kappa B - metabolism Nuclear Proteins Phosphoproteins Repressor Proteins - genetics Repressor Proteins - metabolism Signal Transduction Toll-Like Receptor 6 - genetics Toll-Like Receptor 6 - metabolism Toll-Like Receptors - genetics Toll-Like Receptors - metabolism Transcription Factor RelA - genetics Transcription Factor RelA - metabolism Transcription Factors - genetics Transcription Factors - metabolism
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!