Minimal Clinically Important Difference in Quality of Life for Patients With Low Back Pain

STUDY DESIGN.Multicenter, prospective, cohort study. OBJECTIVE.To estimate the Minimal Clinically Important Difference (MCID) for the physical (PCS) and mental (MCS) component summaries of Short Form SF-12 (SF-12), in patients with low back pain (LBP). SUMMARY OF BACKGROUND DATA.Quality of life is o...

Full description

Saved in:
Bibliographic Details
Published in:Spine (Philadelphia, Pa. 1976) Pa. 1976), 2017-12, Vol.42 (24), p.1908-1916
Main Authors: Díaz-Arribas, María J., Fernández-Serrano, Mónica, Royuela, Ana, Kovacs, Francisco M., Gallego-Izquierdo, Tomás, Ramos-Sánchez, Mabel, Llorca-Palomera, Rosa, Pardo-Hervás, Pedro, Martín-Pariente, Oscar S.
Format: Article
Language:English
Subjects:
Adult
Area Under Curve
Chronic Pain - therapy
Conservative Treatment
Disability Evaluation
Female
Health Status
Humans
Low Back Pain - therapy
Male
Middle Aged
Minimal Clinically Important Difference
Pain Measurement
Prospective Studies
Quality of Life
ROC Curve
Self Report
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:STUDY DESIGN.Multicenter, prospective, cohort study. OBJECTIVE.To estimate the Minimal Clinically Important Difference (MCID) for the physical (PCS) and mental (MCS) component summaries of Short Form SF-12 (SF-12), in patients with low back pain (LBP). SUMMARY OF BACKGROUND DATA.Quality of life is one of the core domains recommended to be assessed in patients with LBP. SF-12 is the most widely used instrument for this purpose, but its MCID was unknown. METHODS.458 patients with subacute and chronic LBP were consecutively recruited across 21 practices. LBP, referred pain, disability, PCS and MCS were assessed upon recruitment and 12 months later. Self-reported health status change between baseline and 12 month-assessment, was used as the external criterion. The MCID for SF-12 was estimated following four anchor-based methods; minimal detectable change (MDC); average change (AC); change difference (CD); and receiver operating characteristic curve (ROC), for which the Area Under the Curve (AUC) was calculated. The effect on MCID values of pain duration and baseline scores was assessed. RESULTS.Values for PCS wereMDC0.56, AC2.71, CD3.29, ROC1.14. Values for MCS, wereMDC3.77, AC3.54, CD1.13, ROC4.23. AUC values were < 0.7. MCID values were smaller among chronic patients and those with better baseline quality of life. CONCLUSIONS.Different methods for MCID calculation lead to different results. In patients with subacute and chronic LBP, improvements > 3.77 in MCS and > 3.29 in PCS, can be considered clinically relevant. MCID is smaller in patients with longer pain duration and better baseline quality of life.Level of Evidence2
ISSN:0362-2436
1528-1159
DOI:10.1097/BRS.0000000000002298