The blood volume of mammals as determined by experiments upon rabbits, guinea-pigs, and mice, and its relationship to the body weight and to the surface area expressed in a formula

The blood volume of animals has for many years been the subject of numerous investigations. This is but natural, considering its great importance for the study of disease. As, however, the results obtained are very discordant, we have determined the blood volumes of rabbits, guinea-pigs, and mice by...

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Bibliographic Details
Published in:Proceedings of the Royal Society of London. Series B, Containing papers of a biological character Containing papers of a biological character, 1910-08, Vol.82 (558), p.545-546
Main Authors: Dreyer, Georges, Ray, William
Format: Article
Language:English
Subjects:
Animals
Blood volume
Body weight
Surface areas
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Summary:The blood volume of animals has for many years been the subject of numerous investigations. This is but natural, considering its great importance for the study of disease. As, however, the results obtained are very discordant, we have determined the blood volumes of rabbits, guinea-pigs, and mice by Welcker’s methos, by washing out the circulating system, and by following the percentage fall of hæmoglobin after bleeding. Our experiments have given the following results:- (1) The blood volume of living mammals can be determined very accurately by bleeding the animals (about 20 percent. of its original blood volume) and determining the percentage fall of hæmoglobin at the moment when equilibrium is reached. This method gives results remarkably concordant with those obtained by washing out the circulating system. In employing this method it is absolutely essential that the animals that the animals should not have been bled before.
ISSN:0950-1193
2053-9185
DOI:10.1098/rspb.1910.0048