Sex‐specific behavioural, metabolic, and immunohistochemical changes after repeated administration of the synthetic cannabinoid AKB48 in mice

AKB48 is a synthetic cannabinoid illegally sold for its psychoactive cannabis-like effects that have been associated with acute intoxication and whose effects are poorly known. Using a behavioural, neurochemical, and immunohistochemical approach, we investigated the pharmaco-toxicological effects, p...

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Bibliographic Details
Published in:British journal of pharmacology 2024-05, Vol.181 (9), p.1361-1382
Main Authors: Corli, Giorgia, Roda, Elisa, Tirri, Micaela, Bilel, Sabrine, De Luca, Fabrizio, Strano‐Rossi, Sabina, Gaudio, Rosa Maria, De‐Giorgio, Fabio, Fattore, Liana, Locatelli, Carlo Alessandro, Marti, Matteo
Format: Article
Language:English
Subjects:
Acute intoxication
Analgesia
Blood levels
Body temperature
Cannabinoid CB1 receptors
Cannabinoids
Cannabis
Cerebellum
Females
Injection
Intoxication
Males
Neuroplasticity
Pharmacodynamics
Pharmacokinetics
Sensorimotor system
Sex
Sex differences
Sexes
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