Functionalization of C(sp³)-H bonds using a transient directing group

Proximity-driven metalation has been extensively exploited to achieve reactivity and selectivity in carbon–hydrogen (C–H) bond activation. Despite the substantial improvement in developing more efficient and practical directing groups, their stoichiometric installation and removal limit efficiency a...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2016-01, Vol.351 (6270), p.252-256
Main Authors: Zhang, Fang-Lin, Hong, Kai, Li, Tuan-Jie, Park, Hojoon, Yu, Jin-Quan
Format: Article
Language:English
Subjects:
Aldehydes
Amino acids
Carbon
Catalysis
Chemistry
Hydrogen
Ketones
Metals
Palladium
Rhodium
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