Three-component synthesis of spiro compounds with a carbamate functionality

1,3-Dipolar cycloaddition of methyl 4-[2-(2-oxo-1,2-dihydro-3 H -indol-3-ylidene)acetyl]phenylcarbamate to non-stabilized azomethine ylides generated by decarboxylation of α-amino acid (sarcosine and proline) adducts with ketones (isatin and ninhydrin) occurred regioselectively with formation of the...

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Bibliographic Details
Published in:Russian journal of organic chemistry 2011-03, Vol.47 (3), p.402-404
Main Authors: Velikorodov, A. V., Poddubnyi, O. Yu, Krivosheev, O. O., Titova, O. L.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Organic Chemistry
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Summary:1,3-Dipolar cycloaddition of methyl 4-[2-(2-oxo-1,2-dihydro-3 H -indol-3-ylidene)acetyl]phenylcarbamate to non-stabilized azomethine ylides generated by decarboxylation of α-amino acid (sarcosine and proline) adducts with ketones (isatin and ninhydrin) occurred regioselectively with formation of the corresponding spiro compounds having a carbamate moiety.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428011030122