Motor Unit Synchronization Is Increased in Biceps Brachii After Exercise-Induced Damage to Elbow Flexor Muscles

• Published in: Journal of neurophysiology 2008-02, Vol.99 (2), p.1008-1019
• Main Authors: Dartnall, Tamara J, Nordstrom, Michael A, Semmler, John G
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Analysis of Variance; Biomechanical Phenomena; Brachial Plexus - pathology; Elbow; Electromyography - methods; Exercise; Female; Humans; Male; Motor Neurons - physiology; Muscle Contraction - physiology; Muscle, Skeletal - injuries; Muscle, Skeletal - physiopathology; Task Performance and Analysis; Time Factors
• ISSN: 0022-3077; 1522-1598
• DOI: 10.1152/jn.00686.2007

Discipline of Physiology and Research Centre for Human Movement Control, School of Molecular and Biomedical Science, The University of Adelaide, Adelaide, Australia Submitted 21 June 2007; accepted in final form 28 December 2007 The purpose of this study was to determine the effect of eccentric exercise on correlated motor unit discharge (motor unit synchronization and coherence) during low-force contractions of the human biceps brachii muscle. Eight subjects (age, 25 ± 7 yr) performed three tasks involving isometric contraction of elbow flexors while EMG (surface and intramuscular) records were obtained from biceps brachii. Tasks were 1 ) maximum voluntary contraction (MVC); 2 ) constant-force contraction at various submaximal targets; and 3 ) sustained discharge of pairs of concurrently active motor units for 2–5 min. These tasks were performed before, immediately after, and 24 h after fatiguing eccentric exercise. MVC force declined 46% immediately after eccentric exercise and remained depressed (31%) 24 h later, which is indicative of muscle damage. For the constant-force task, biceps brachii EMG ( 100% greater) and force fluctuations ( 75% greater) increased immediately after exercise, and both recovered by 50% 24 h later. Motor unit synchronization, quantified by cross-correlation of motor unit pairs during low-force (1–26% MVC) contractions, was 30% greater immediately after ( n = 105 pairs) and 24 h after exercise ( n = 92 pairs) compared with before exercise ( n = 99 pairs). Similarly, motor unit coherence at low (0–10 Hz) frequencies was 20% greater immediately after exercise and 34% greater 24 h later. These results indicate that the series of events leading to muscle damage from eccentric exercise alters the correlated behavior of human motor units in biceps brachii muscle for 24 h after the exercise. Address for reprint requests and other correspondence: J. G. Semmler, School of Molecular and Biomedical Science, The Univ. of Adelaide, Adelaide, South Australia 5005, Australia (E-mail: john.semmler{at}adelaide.edu.au )