Validation Study of the Italian Addenbrooke’s Cognitive Examination Revised in a Young-Old and Old-Old Population

• Published in: Dementia and geriatric cognitive disorders 2011-01, Vol.32 (5), p.301-307
• Main Authors: Pigliautile, M., Ricci, M., Mioshi, E., Ercolani, S., Mangialasche, F., Monastero, R., Croce, M.F., Federici, S., Mecocci, P.
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Alzheimer Disease - diagnosis; Alzheimer Disease - psychology; Biological and medical sciences; Cardiovascular system; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - psychology; Cross-Cultural Comparison; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Dementia - diagnosis; Dementia - psychology; Dementia, Vascular - diagnosis; Dementia, Vascular - psychology; Female; Frontotemporal Dementia - diagnosis; Frontotemporal Dementia - psychology; Humans; Italy; Lewy Body Disease - diagnosis; Lewy Body Disease - psychology; Male; Medical sciences; Mental Status Schedule - statistics & numerical data; Neurology; Neuropsychological Tests - statistics & numerical data; Original Research Article; Pharmacology. Drug treatments; Psychometrics - statistics & numerical data; Reference Values; Reproducibility of Results; Translating; Vasodilator agents. Cerebral vasodilators
• ISSN: 1420-8008; 1421-9824
• DOI: 10.1159/000334657

Aims: The main aims of the study were the translation and the subsequent validation in Italian of the Addenbrooke’s Cognitive Examination Revised (ACE-R), and the evaluation of its usefulness in discriminating cognitively normal subjects from patients with mild dementia in an elderly population. Methods: The ACE-R was translated and adapted into Italian. The Italian ACE-R was administered to a group of 179 elderly subjects (72 cognitively healthy and 107 subjects with mild dementia, mean age 75.4 ± 6.4 years). The group was stratified into two subsamples according to age, i.e. a young-old (