Abstract P016: Physical Activity as Key Risk Factors for Incident Dementiain a Thai Population: Health Checks Ubon Ratchathani (HCUR) Study

• Published in: Circulation (New York, N.Y.) N.Y.), 2018-03, Vol.137 (suppl_1)
• Main Authors: Chamnan, Parinya, Boongird, Prasert, Laptikultham, Somsak, Nitiyanont, Wannee, Aekplakorn, Wichai
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.137.suppl_1.p016

Abstract only Introduction: There is little evidence to describe risk factors for dementia in a Thai general population. Hypothesis: This study was aimed to examine factors associated with the risk of developing dementia in a Thai general population in Ubon Ratchathani. Methods: Data on 761,935 men and women participating in the Health Check Ubon Ratchathani (HCUR) Project in 2006-7 were merged with diagnostic information from hospital’s electronic medical records in the following 5 years (2006-2012). Using a retrospective cohort study design, we examined the incidence of physician-diagnosed dementia over 5 years. Factors independently associated with the risk of developing dementia were examined using multivariate cox proportional hazard regression. Results: Over a total time at risk of 4,407,201 person-years, 519 individuals developed dementia, the incidence rate of dementia was 0.12 (95%CI 0.11-0.13) per 1,000 person-years. Factors independently associated with the risk of developing dementia in multivariate cox regression included increasing age, diabetes and lack of physical exercise. The risk of dementia rose by 9% for every one year of age older (Hazard ratio (HR) of 1.09 (1.08-1.09), p