Abstract 16792: Gender Differences in African Americans and Caucasians With Severe Aortic Stenosis or Bicuspid Aortic Valve

• Published in: Circulation (New York, N.Y.) N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A16792-A16792
• Main Authors: White Solaru, Khendi T, Popovic, Zoran, Kalahasti, Vidyasagar, Roselli, Eric, Barzilai, Benico
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.138.suppl_1.16792

IntroductionSevere aortic stenosis (AS) is a multifactorial, progressive condition that is associated with high short-term mortality. Risk factors for mortality have been described and include male sex, hypertension, hyperlipidemia, and congenital bicuspid valve (BAV). Senile, calcific AS is thought to affect both genders equally in contrast to BAV which has a 3:1 male preponderance. It is unknown if there are gender differences in the prevalence of severe, senile AS or congenital bicuspid aortic valve in Whites compared to Blacks.Methods10,299 Black or White patients with severe aortic stenosis or bicuspid aortic valve treated at Cleveland Clinic with primary AVR from 1/1/2000 to 1/1/2017 were included in this study. There were 257 Black patients (2.5% of the study population). Categorical data on gender was compared using the Chi-squared test.ResultsBlacks with severe aortic stenosis were significantly more likely to be female compared to Caucasians (55% vs 36%, p