Abstract 13165: Self-Reported Social Functioning is Responsive to Change in Functional Class in Patients With a Left Ventricular Assist Device: Findings From the Mechanical Circulatory Support Measures of Adjustment and Quality of Life Study

• Published in: Circulation (New York, N.Y.) N.Y.), 2020-11, Vol.142 (Suppl_3 Suppl 3), p.A13165-A13165
• Main Authors: Hahn, Elizabeth A, Cummings, Peter D, Wortman, Katy, Lindenfeld, Joann, Teuteberg, Jeffrey, Kiernan, Michael S, Allen, Larry A, McIlvennan, Colleen K, Lee, Christopher S, Denfeld, Quin E, Klein, Liviu, Beiser, David, Murks, Catherine M, Rich, Jonathan D, Pham, Duc T, Yancy, Clyde W, Cella, David, Walsh, Mary N, Ruo, Bernice, Buono, Sarah K, Grady, Kathleen L
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.142.suppl_3.13165

IntroductionImprovement in social functioning is an important goal for advanced heart failure (HF) patients (pts) who receive left ventricular assist devices (LVADs). Self-reported social functioning and its association with clinical change is understudied. MethodsAdult HF pts who received LVADs at nine U.S. sites completed two measures of social functioning prior to, and 3-6 months after, surgery. Patient-Reported Outcomes Measurement Information System (PROMIS) measures wereAbility to Participate in Social Roles and Activities (Ability) and Satisfaction with Social Roles and Activities (Satisfaction). PROMIS uses T-scores standardized to a U.S. general population (mean=50; standard deviation, SD=10); higher scores represent better outcomes. New York Heart Association (NYHA) Functional Classification was assigned at both times by treating clinicians; change was subsequently categorized as Better, Same or Worse NYHA. Linear mixed effects models and least-squares means were estimated for Ability and Satisfaction. ResultsPts (n=107) were primarily male (78%) and non-Hispanic White (68%); mean age (SD)=54 (12.5) years; 74% were NYHA Class IV prior to surgery and only 18% were NYHA IV at follow-up. NYHA was better for the majority (n=75, 70%); 24% (n=26) were the same, and 6% (n=6) were worse. Mean Ability and Satisfaction were lower than the general population mean of 50 at both time points (Figure). Ability improved for the NYHA Better (p