Abstract 12330: The Degree of Common Carotid Artery Stenosis and the Risk of Cardiovascular Disease Incidence in the Suita Study

• Published in: Circulation (New York, N.Y.) N.Y.), 2021-11, Vol.144 (Suppl_1), p.A12330-A12330
• Main Authors: Teramoto, Masayuki, Kokubo, Yoshihiro, Arafa, Ahmed, Sheerah, Haytham, Nakao, Yoko, Sakai, Yukie, Watanabe, Emi, Li, Jiaqi, Honda-Kohmo, Kyoko, Kashima, Rena, Kataoka, Hiroharu
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.144.suppl_1.12330

IntroductionLittle is known about whether common carotid artery (CCA) stenosis is associated with the risk of incident cardiovascular diseases (CVD) in a general population. We aimed to examine the impact of CCA stenosis degree on incident CVD in a general population. MethodsWe studied 5,133 Japanese men and women (mean age 59.7 years) without CVD whose CCA was measured by carotid ultrasonography on both sides at baseline (April 1994 to March 2005). We confirmed stenosis by color Doppler and calculated the stenosis degree as a percentage of the stenotic area of the lumen in the cross-section perpendicular to the long axis. The Cox proportional hazard model was used to calculate the multivariable-adjusted hazard ratios (HRs) with 95% confidence intervals (CIs) of CVD and its subtypes for people with CCA stenosis ≥50 % and 25-49 % compared to those with CCA stenosis