Abstract 129: Enrolling Spanish-Speaking Subjects into Prehospital Research: The FAST-MAG Spanish Line Experience

• Published in: Stroke (1970) 2013-02, Vol.44 (suppl_1)
• Main Authors: Sanossian, Nerses, Starkman, Sidney, Ali, Latisha K, Restrepo, Lucas, Valdes-Sueiras, Miguel, Liebeskind, David S, Chatfield, Fiona, Hodgson, T. Keta, Cherin, Samantha, Saver, Jeffrey L
• Format: Article
• Language: English
• ISSN: 0039-2499; 1524-4628
• DOI: 10.1161/str.44.suppl_1.A129

Abstract only Background: Clinical trials should enroll diverse subjects who are representative of the general population. Enrollment in other languages requires substantial effort, including language-specific consent forms and physician-investigators fluent in language of consent. We describe the yield of a dedicated 24-hour Spanish prehospital research enrollment line. Methods: FAST-MAG is a phase 3, NIH-funded, randomized, placebo-control study of prehospital magnesium sulfate within 2 hours of stroke onset. The study is being conducted in Los Angeles and Orange Counties, home to 12.9 million people of whom just under half (44.8%) identify as Hispanic or Latino. Each of the 353 study ambulances carries: 1) 8 consent forms, 4 in English and 4 in Spanish, for the vehicle’s 4 most common destination hospitals; and 2) a cell phone with a quick-dial button for English and Spanish-speaking physician-investigator. Results: Data was available on 854 consecutive enrolments of whom 141 (17%) were via the Spanish and 713 (83%) via the English line. Patients enrolled via the Spanish line were younger (65 vs 70 years, p