Abstract WMP110: Improvement in Cortical Versus Subcortical Perfusion After Superficial Temporal Artery- Middle Cerebral Artery (MCA) Bypass in Patients With Severe Stenosis of Intracranial Carotid and MCA

Abstract only Background and Objective: The role of superficial temporal artery-middle cerebral artery (STA-MCA) bypass in patients with symptomatic intracranial steno-occlusive disease has been evaluated scarcely. We have recently reported the improvement in clinical and various cerebral hemodynami...

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Published in:Stroke (1970) 2016-02, Vol.47 (suppl_1)
Main Authors: Sharma, Vijay K, Bolem, Nagarjun, Chow, Ning, Wong, Lily Y, Teoh, Hock-Luen, Chan, Bernard P, Yeo, Tseng-Tsai, Seet, Raymond, Sinha, Arvind K
Format: Article
Language:English
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Summary:Abstract only Background and Objective: The role of superficial temporal artery-middle cerebral artery (STA-MCA) bypass in patients with symptomatic intracranial steno-occlusive disease has been evaluated scarcely. We have recently reported the improvement in clinical and various cerebral hemodynamic parameters after STA-MCA bypass surgery for severe steno-occlusive disease of intracranial internal carotid (ICA) or middle cerebral artery (MCA) and impaired cerebral vasodilatory reserve (CVR). Using acetazolamide challenged hexamethylpropyleneamine-oxime single-photon emission computed tomography (HMPAO-SPECT), we evaluated the differential improvement in metabolic perfusion in cortical and subcortical structures after STA-MCA bypass surgery. Methods: Patients with severe steno-occlusive disease of intracranial ICA or MCA underwent transcranial Doppler (TCD) for CVR assessment using breath-holding index (BHI). Patients with impaired BHI (
ISSN:0039-2499
1524-4628
DOI:10.1161/str.47.suppl_1.wmp110