Abstract TP324: Macrobleeds and Microbleeds: A Vascular Risk Factor Microangiopathy

Abstract only Background: The predominant type of cerebral small vessel disease (SVD) and clinical outcomes of patients who present with a combination of lobar and deep intracerebral hemorrhage (ICH)/microbleed (MB) locations (Mixed-ICH, see figure) is unknown. Methods: Out of 391 consecutive ICH, 7...

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Published in:Stroke (1970) 2017-02, Vol.48 (suppl_1)
Main Authors: Pasi, Marco, Charidimou, Andreas, Boulouis, Gregoire, Auriel, Eitan, Haley, Kellen, Ayres, Alison, Schwab, Kristin, Goldstein, Joshua, Rosand, Jonathan, Viswanathan, Anand, Pantoni, Leonardo, Greenberg, Steven, Gurol, Edip
Format: Article
Language:English
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Summary:Abstract only Background: The predominant type of cerebral small vessel disease (SVD) and clinical outcomes of patients who present with a combination of lobar and deep intracerebral hemorrhage (ICH)/microbleed (MB) locations (Mixed-ICH, see figure) is unknown. Methods: Out of 391 consecutive ICH, 75 (19%) had Mixed-ICH, and their demographics, clinical/laboratory features, and SVD neuroimaging markers were compared to 191 probable Cerebral Amyloid Angiopathy (CAA-ICH) and 125 strictly deep-MB and ICH (Deep-ICH) patients. ICH-recurrence on follow up was also analyzed. Results: Mixed-ICH patients had a higher prevalence of hypertension, diabetes, left ventricular hypertrophy rates, higher creatinine values, as well as more prevalent lacunes and basal ganglia (BG) enlarged perivascular spaces (EPVS) than CAA-ICH (all p
ISSN:0039-2499
1524-4628
DOI:10.1161/str.48.suppl_1.tp324