Impact of intracranial hypertension and cerebral perfusion pressure on spreading depolarization

Spreading depolarization (SD) develops after stroke and traumatic brain injury and may contribute to secondary brain damage. These diseases are often accompanied by intracranial hypertension, but little is known about the effects of intracranial pressure (ICP) on SD. Here, we study the effect of inc...

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Bibliographic Details

Published in:	Journal of cerebral blood flow and metabolism 2025-04, Vol.45 (4), p.703-716
Main Authors:	Nishimoto, Takuma, Oka, Fumiaki, Inoue, Takao, Moriyama, Hiroshi, Kawano, Reo, Suzuki, Michiyasu, Chung, David Y, Ayata, Cenk, Ishihara, Hideyuki
Format:	Article
Language:	English
Subjects:	Animals Cerebrovascular Circulation - physiology Cortical Spreading Depression - physiology Intracranial Hypertension - metabolism Intracranial Hypertension - physiopathology Intracranial Pressure - physiology Male Neurons - pathology Original Rats Rats, Sprague-Dawley
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