Hospital Mortality and Length of Stay for Patients with Myelodysplastic Syndrome Presenting with Acute ST-Elevation Myocardial Infarction (STEMI)

• Published in: Blood 2021-11, Vol.138 (Supplement 1), p.4674-4674
• Main Authors: Park, Kyeeun, Aung, Pyi Phyo, Carlos, Carracedo Uribe, Himed, Khaled, Yu, Jisang, Jacob, Jeffy
• Format: Article
• Language: English
• ISSN: 0006-4971; 1528-0020
• DOI: 10.1182/blood-2021-154060

Introduction Ischemic heart disease remains the single largest cause of death worldwide. In the USA, 365,744 deaths were associated to coronary heart disease, and the mortality is highest in population older than 65 years old. Myelodysplastic syndromes (MDS) also mainly affect this group age and studies suggest an incidence as high as 75 cases per 100,000 aged >65 years. In the following abstract we analyze the mortality rate in patients with MDS and STEMI. Methods We conducted a retrospective analysis of 3 years of National inpatient sample (HCUP-NIS) data base from 2016 to 2018. Patients older than 60 years old and with or without MDS were selected using ICD-10 diagnosis code. Principal diagnosis of STEMI was included with the code. ICD-10 procedure code was used for left heart catheterization. Discharge-level weight analysis was used to produce a national estimate. Continuous variables were compared by t-test, while chi-square and Fisher's exact test were used for categorical variables. Finally, multivariate logistic regression was used to calculate odds ratio for inpatient mortality and multivariate linear regression for length of stay using STATA 17 statistical software. Results A total of 45,724,104 admissions met inclusion criteria, of those, 210,780 patients (0.46 %) have MDS. Patients with MDS are more likely to be of older age (78.7 v 74.8, p