Case Report: Invasive candidiasis of the head and neck in a five-month-old infant: A case study [version 1; peer review: awaiting peer review]

Invasive sino-orbital fungal infection is an uncommon, yet severe condition that predominantly affects individuals with compromised immune systems. In this study, we report the case of a 5-month-old immunocompetent infant who exhibited persistent dacryocystitis despite receiving broad-spectrum antib...

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Bibliographic Details
Published in:F1000 research 2024, Vol.13, p.1232
Main Authors: Mezri, Sameh, Laabidi, Eya, Zitouni, Chaima, Thabet, Wadii
Format: Article
Language:English
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Summary:Invasive sino-orbital fungal infection is an uncommon, yet severe condition that predominantly affects individuals with compromised immune systems. In this study, we report the case of a 5-month-old immunocompetent infant who exhibited persistent dacryocystitis despite receiving broad-spectrum antibiotics. Subsequently, the patient developed ethmoiditis, orbital subperiosteal abscess, and ulceration of the hard palate. Mycological and histological samples were indicative of Candida infections. The patient underwent sinus surgery and surgical debridement, along with antifungal therapy. The treatment was successful, and the follow-up was uneventful for up to 6 months. To our knowledge, this is the first reported case of invasive sino-orbital candidiasis in an immunocompetent infant with dacryocystitis as the entry point. This study explores the clinical features, management approaches, and outcomes of this potentially fatal disease.
ISSN:2046-1402
2046-1402
DOI:10.12688/f1000research.156343.1