Resolution of Pulmonary Hypertension with Low-Molecular-Weight Heparin, Steroid, and Prostacyclin Analogue Therapy: Could it be Early-Phase Pulmonary Veno-Occlusive Disease?

Pulmonary veno-occlusive disease (PVOD) is a rare cause of pulmonary hypertension. The authors present a case of neuroblastoma with progressive dyspnea, hypoxemia, and pulmonary hypertension. A computed tomography scan of the chest revealed septal thickening and diffuse micronodules. The patient was...

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Published in:Pediatric hematology and oncology 2011-09, Vol.28 (6), p.529-534
Main Authors: Yildirim, Zuhal Keskin, Sepetcigil, Oguzhan, Karacan, Mehmet, Kantarci, Mecit, Buyukavci, Mustafa
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - administration & dosage
Anticoagulants - administration & dosage
Antihypertensive Agents
Child, Preschool
children
Epoprostenol - administration & dosage
Epoprostenol - analogs & derivatives
Heparin, Low-Molecular-Weight - administration & dosage
Humans
Hypertension, Pulmonary - diagnostic imaging
Hypertension, Pulmonary - drug therapy
Hypertension, Pulmonary - etiology
Male
neuroblastoma
Neuroblastoma - complications
Neuroblastoma - diagnostic imaging
Neuroblastoma - drug therapy
pulmonary hypertension
pulmonary veno-occlusive disease
Pulmonary Veno-Occlusive Disease - diagnostic imaging
Pulmonary Veno-Occlusive Disease - drug therapy
Pulmonary Veno-Occlusive Disease - etiology
Radiography
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Summary:Pulmonary veno-occlusive disease (PVOD) is a rare cause of pulmonary hypertension. The authors present a case of neuroblastoma with progressive dyspnea, hypoxemia, and pulmonary hypertension. A computed tomography scan of the chest revealed septal thickening and diffuse micronodules. The patient was diagnosed as PVOD and was successfully treated with low-molecular-weight heparin (LMWH) and corticosteroid.
ISSN:0888-0018
1521-0669
DOI:10.3109/08880018.2011.570417