When the Last Line Fails: Characterization of Colistin-Resistant Acinetobacter baumannii Reveals High Virulence and Limited Clonal Dissemination in Greek Hospitals

Acinetobacter baumannii has emerged as a major pathogen responsible for healthcare-associated infections, particularly in intensive care units, contributing to significant morbidity and mortality due to its multidrug resistance and ability to persist in clinical environments. This study aimed to inv...

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Bibliographic Details
Published in:	Pathogens (Basel) 2025-07, Vol.14 (8), p.730
Main Authors:	Karakalpakidis, Dimitrios, Papadopoulos, Theofilos, Paraskeva, Michalis, Tsitlakidou, Michaela-Eftychia, Vagdatli, Eleni, Katsifa, Helen, Beloukas, Apostolos, Kotzamanidis, Charalampos, Kottaridi, Christine
Format:	Article
Language:	English
Subjects:	Acinetobacter baumannii Acinetobacter baumannii - drug effects Acinetobacter baumannii - genetics Acinetobacter baumannii - isolation & purification Acinetobacter baumannii - pathogenicity Acinetobacter Infections - drug therapy Acinetobacter Infections - epidemiology Acinetobacter Infections - microbiology Anti-Bacterial Agents - pharmacology Antimicrobial agents Antimicrobial resistance Biofilms Colistin Colistin - pharmacology colistin resistant Cross Infection - epidemiology Cross Infection - microbiology Disease control Drug resistance Drug resistance in microorganisms Drug Resistance, Multiple, Bacterial - genetics E coli Electrophoresis Epidemiology Genes Genomics Germany Greece Greece - epidemiology Health aspects Hospitals Humans Infection Infections Intensive care units mcr genes Microbial Sensitivity Tests Morbidity Mortality Motility Multidrug resistance Multidrug resistant organisms Pathogens Patients PFGE Polymerase chain reaction Pulsed-field gel electrophoresis Robust control Surveillance Swarming Twitching Virulence Virulence (Microbiology) Virulence - genetics Virulence Factors - genetics virulence genes
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