Is fat mass & obesity-associated (FTO) gene master regulator of obesity ?

In 2007, using GWAS, a UK research team led by Dr Andrew Hattersley of Peninsula Medical School in Exeter discovered a gene variant that showed strong link with body mass index (BMI)[3]. [...]the association between FTO and obesity appears to be due to its influence on expression of IRX3 [Figure 1]....

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Bibliographic Details
Published in:Indian journal of medical research (New Delhi, India : 1994) India : 1994), 2016-03, Vol.143 (3), p.264-266
Main Authors: Mittal, Balraj, Srivastava, Apurva, Srivastava, Neena
Format: Article
Language:English
Subjects:
Adipocytes
Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics
Body Mass Index
Diabetes
Energy Intake
Female
Genes
Genetic aspects
Genetic Predisposition to Disease
Genetic regulation
Genome-Wide Association Study
Genotype
Health aspects
Homeodomain Proteins - genetics
Humans
Male
Obesity
Obesity - genetics
Polymorphism, Single Nucleotide
Population
Studies
Transcription Factors - genetics
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