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Characterization of scrotal involvement in children and adolescents with IgA vasculitis

To characterize scrotal involvement in children and adolescents with IgA vasculitis. A cross-sectional retrospective study included 296 IgA vasculitis (EULAR/PRINTO/PRES criteria) patients, 150/296 (51%) were males and assessed by demographic/clinical/laboratory and treatments. Scrotal involvement w...

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Bibliographic Details
Published in:Advances in rheumatology (London, England) England), 2018-11, Vol.58 (1), p.38-38, Article 38
Main Authors: Buscatti, Izabel M, Abrão, Henrique M, Kozu, Katia, Marques, Victor L S, Gomes, Roberta C, Sallum, Adriana M E, Silva, Clovis A
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Language:English
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Summary:To characterize scrotal involvement in children and adolescents with IgA vasculitis. A cross-sectional retrospective study included 296 IgA vasculitis (EULAR/PRINTO/PRES criteria) patients, 150/296 (51%) were males and assessed by demographic/clinical/laboratory and treatments. Scrotal involvement was defined by the presence of scrotal edema and/or pain/tenderness in physical examination and/or testicular Doppler ultrasound abnormalities. Scrotal involvement was observed in 28/150 (19%) IgA vasculitis patients. This complication was evidenced at IgA vasculitis diagnosis in 27/28 (96%). Acute recurrent scrotal involvement was observed in 2/150 (1%) and none had chronic subtype. Further analysis of patients with scrotal involvement at first episode (n = 27) compared to those without this complication (n = 122) revealed that the median age at diagnosis [4.0 (2.0-12) vs. 6 (1.3-13) years, p = 0.249] was similar in both groups. The frequency of elevated serum IgA was significantly lower in IgA vasculitis patients with scrotal involvement versus without this manifestation (18% vs. 57%, p = 0.017), whereas glucocorticoid (93% vs. 49%, p 
ISSN:2523-3106
2523-3106
DOI:10.1186/s42358-018-0039-3