Carotid artery velocity time integral and corrected flow time measured by a wearable Doppler ultrasound detect stroke volume rise from simulated hemorrhage to transfusion

Doppler ultrasonography of the common carotid artery is used to infer stroke volume change and a wearable Doppler ultrasound has been designed to improve this workflow. Previously, in a human model of hemorrhage and resuscitation comprising approximately 50,000 cardiac cycles, we found a strong, lin...

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Bibliographic Details
Published in:BMC research notes 2022-01, Vol.15 (1), p.7-7, Article 7
Main Authors: Kenny, Jon-Émile S, Barjaktarevic, Igor, Mackenzie, David C, Elfarnawany, Mai, Yang, Zhen, Eibl, Andrew M, Eibl, Joseph K, Kim, Chul-Ho, Johnson, Bruce D
Format: Article
Language:English
Subjects:
Blood Flow Velocity
Blood transfusions
Body mass index
Carotid arteries
Carotid Arteries - diagnostic imaging
Carotid artery
Carotid Artery, Common
Carotid Doppler
Corrected flow time
Diagnosis
Doppler effect
Hemorrhage
Humans
Medical examination
Research Note
Risk factors
Stroke (Disease)
Stroke Volume
Ultrasonic imaging
Ultrasonography, Doppler
Ultrasound
Veins & arteries
Velocity
Velocity time integral
Wearable Electronic Devices
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Summary:Doppler ultrasonography of the common carotid artery is used to infer stroke volume change and a wearable Doppler ultrasound has been designed to improve this workflow. Previously, in a human model of hemorrhage and resuscitation comprising approximately 50,000 cardiac cycles, we found a strong, linear correlation between changing stroke volume, and measures from the carotid Doppler signal, however, optimal Doppler thresholds for detecting a 10% stroke volume change were not reported. In this Research Note, we present these thresholds, their sensitivities, specificities and areas under their receiver operator curves (AUROC). Augmentation of carotid artery maximum velocity time integral and corrected flowtime by 18% and 4%, respectively, accurately captured 10% stroke volume rise. The sensitivity and specificity for these thresholds were identical at 89% and 100%. These data are similar to previous investigations in healthy volunteers monitored by the wearable ultrasound.
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-021-05896-y