Speckle Tracking Echocardiography in Patients with Non-Ischemic Dilated Cardiomyopathy Who Undergo Cardiac Resynchronization Therapy: A Narrative Review

Non-ischemic dilated cardiomyopathy (DCM) represents a significant cause of heart failure, defined as the presence of left ventricular (LV) dilatation and systolic dysfunction unexplained solely by abnormal loading conditions or coronary artery disease. Cardiac resynchronization therapy (CRT) has em...

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Bibliographic Details
Published in:Diagnostics (Basel) 2024-06, Vol.14 (11), p.1178
Main Authors: Antoniou, Nikolaos, Kalaitzoglou, Maria, Tsigkriki, Lamprini, Baroutidou, Amalia, Tsaousidis, Adam, Koulaouzidis, George, Giannakoulas, George, Charisopoulou, Dafni
Format: Article
Language:English
Subjects:
cardiac resynchronization therapy
Cardiomyopathy
Cardiomyopathy, Dilated
Care and treatment
Coronary heart disease
Deformation
Doppler effect
dyssynchrony
Echocardiography
Ejection fraction
Heart
Heart failure
Ischemia
Magnetic resonance imaging
Mechanics
Medical prognosis
non-ischemic dilated cardiomyopathy
Patients
Review
speckle tracking echocardiography
strain
strain rate
Velocity
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Summary:Non-ischemic dilated cardiomyopathy (DCM) represents a significant cause of heart failure, defined as the presence of left ventricular (LV) dilatation and systolic dysfunction unexplained solely by abnormal loading conditions or coronary artery disease. Cardiac resynchronization therapy (CRT) has emerged as a cornerstone in the management of heart failure, particularly in patients with DCM. However, identifying patients who will benefit the most from CRT remains challenging. Speckle tracking echocardiography (STE) has garnered attention as a non-invasive imaging modality that allows for the quantitative assessment of myocardial mechanics, offering insights into LV function beyond traditional echocardiographic parameters. This comprehensive review explores the role of STE in guiding patient selection and optimizing outcomes in CRT for DCM. By assessing parameters such as LV strain, strain rate, and dyssynchrony, STE enables a more precise evaluation of myocardial function and mechanical dyssynchrony, aiding in the identification of patients who are most likely to benefit from CRT. Furthermore, STE provides valuable prognostic information and facilitates post-CRT optimization by guiding lead placement and assessing response to therapy. Through an integration of STE with CRT, clinicians can enhance patient selection, improve procedural success rates, and ultimately, optimize clinical outcomes in patients with DCM. This review underscores the pivotal role of STE in advancing personalized management strategies for DCM patients undergoing CRT.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics14111178