A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report

Desmoid tumors are a rare entity, especially in the pediatric population. There are no reports of such a tumor in newborns. They are associated with high rates of morbidity and mortality, even though they are benign soft tissue tumors. This is due to them exhibiting locally aggressive growth with th...

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Bibliographic Details
Published in:Life (Basel, Switzerland) Switzerland), 2025-01, Vol.15 (1), p.123
Main Authors: Margarint, Irina Maria, Youssef, Tammam, Filip, Cristina, Bizubac, Ana-Mihaela, Popescu, Alexandru, Rotaru, Iulian, Untaru, Olguta, Manolache, Stefan, Iliescu, Vlad Anton, Vladareanu, Radu
Format: Article
Language:English
Subjects:
Abdomen
Aorta
aortic coarctation
Blood pressure
Bronchus
Carotid arteries
Chemotherapy
Coronary vessels
desmoid tumor
Hemodynamics
Localization
Mechanical ventilation
Morbidity
Neonates
newborn
Ostomy
Patients
Pediatrics
Pulmonary arteries
Pulmonary artery
respiratory failure
Review
Soft tissues
Surgery
Tracheostomy
Tumors
Veins & arteries
Ventilators
Weaning
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Summary:Desmoid tumors are a rare entity, especially in the pediatric population. There are no reports of such a tumor in newborns. They are associated with high rates of morbidity and mortality, even though they are benign soft tissue tumors. This is due to them exhibiting locally aggressive growth with the compression or invasion of adjacent structures. Abdominal localization is most commonly reported, although there are reports of mediastinal desmoid tumors. We present the case of a 6-day male patient with a mediastinal desmoid tumor that led to severe aortic coarctation with hemodynamic instability. The tumor also compressed the left pulmonary artery and obstructed the left main bronchus. The initial management consisted of successful emergency surgery with partial resection of the tumor mass and coarctation repair. In the postoperative setting, the patient evolved with severe respiratory dysfunction which was managed with tracheostomy, allowing weaning the child from the mechanical ventilation one month after surgery, along with chemotherapy. We also review the literature, focusing on the management of desmoid tumors.
ISSN:2075-1729
2075-1729
DOI:10.3390/life15010123