Association between depression and HIV treatment outcomes in a US military population with HIV infection

Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcome...

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Published in:AIDS research and therapy 2021-05, Vol.18 (1), p.29-29, Article 29
Main Authors: Carney, Brandon, Daniels, Colton, Xu, Xiaohe, Sunil, Thankam, Ganesan, Anuradha, Blaylock, Jason M, Kronmann, Karl C, Schofield, Christina, Lalani, Tahaniyat, Agan, Brian, Okulicz, Jason F
Format: Article
Language:English
Subjects:
Adherence
African Americans
Age
AIDS/HIV
Antiretroviral agents
Antiretroviral therapy
Care and treatment
Clinical outcomes
Demographics
Depression
Depression, Mental
Diagnosis
Epidemiology
HIV
HIV infection
Human immunodeficiency virus
Mental depression
Mental disorders
Mental health
Minority & ethnic groups
Psychological aspects
Short Report
Viral load suppression
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Summary:Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression. Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, and self-reported adherence (SRA) were included. ART use was defined as ART initiation between 2006 and 2010, with follow-up through 2015. SRA was defined as taking 95% of ART doses and continuous ART was defined as longitudinal ART use with gaps  
ISSN:1742-6405
1742-6405
DOI:10.1186/s12981-021-00350-2