Prognostic Factors for Cognitive Recovery Beyond Early Poststroke Cognitive Impairment (PSCI): A Prospective Cohort Study of Spontaneous Intracerebral Hemorrhage

Poststroke cognitive impairment (PSCI) has been increasingly recognized in patients, but some stroke survivors appear to show cognitive improvement beyond the acute stage. The risk factors associated with cognitive recovery after spontaneous intracerebral hemorrhage (ICH) onset have not yet been suf...

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Bibliographic Details
Published in:Frontiers in neurology 2020-04, Vol.11, p.278-278
Main Authors: Gong, Li, Gu, Yongzhe, Yu, Qiuyue, Wang, Haichao, Zhu, Xiaoping, Dong, Qiong, Xu, Rong, Zhao, Yanxin, Liu, Xueyuan
Format: Article
Language:English
Subjects:
dementia
intracerebral hemorrhage
Neurology
poststroke cognitive impairment
red blood cell
stroke
vascular cognitive impairment
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Summary:Poststroke cognitive impairment (PSCI) has been increasingly recognized in patients, but some stroke survivors appear to show cognitive improvement beyond the acute stage. The risk factors associated with cognitive recovery after spontaneous intracerebral hemorrhage (ICH) onset have not yet been sufficiently investigated in prospective studies. We aimed to identify the trajectory of post-ICH cognitive impairment and the association of potential prognostic factors with follow-up cognitive recovery beyond early PSCI. In this stroke center-based cohort study, 141 consecutive dementia-free patients with spontaneous ICH were included and underwent Montreal Cognitive Assessment (MoCA) evaluation for cognitive function at baseline (within 2 weeks of ICH onset) and the shortened MoCA (short-MoCA) at a 6-month follow-up. To explore the prognostic factors associated with trajectory of cognition after an ICH onset, we adjusted for demographic and vascular risk factors, using multivariate logistic regression analysis. Of the 141 ICH patients, approximately three quarters (106/141) were diagnosed with early PSCI (MoCA score
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2020.00278